Lost in Translation: Ribosome-Associated mRNA and Protein Quality Controls
نویسندگان
چکیده
منابع مشابه
investigating cda tendency and critical thinking abilities of iranian translation students in relation to their translation quality
امروزه مسئله ی اساسی در رویکرد های جدید زبانشناسی، ابعاد اجتماعی و ایدئولوژیک زبان تلقی می شود. گروه های مختلف اجتماعی، سیاسی و یا مذهبی از زبان به عنوان ابزاری برای دستیابی به اهداف درون گروهی خود استفاده می کنند (ون دایک، 2003). آنها معولا ایدئولوژی خود را صریحا ابراز نمی کنند بلکه آن را در غالب کلمات و ساختارهای زبانی پنهان نگه می دارند. تشخیص ایدئولوژی های پنهان در گفتمان نیازمند این موضوع ...
construction and validation of translation metacognitive strategy questionnaire and its application to translation quality
like any other learning activity, translation is a problem solving activity which involves executing parallel cognitive processes. the ability to think about these higher processes, plan, organize, monitor and evaluate the most influential executive cognitive processes is what flavell (1975) called “metacognition” which encompasses raising awareness of mental processes as well as using effectiv...
Ribosome pausing and stacking during translation of a eukaryotic mRNA.
We have devised a sensitive assay to determine the distribution of translating ribosomes on a mRNA. Using this assay to monitor ribosome transit on bovine preprolactin mRNA, we have detected four major positions of ribosome pausing in both wheat-germ and rabbit reticulocyte extracts. Two of these rate-limiting steps represent initiation and termination. One pause occurs after approximately 75 a...
متن کاملA max-plus model of ribosome dynamics during mRNA translation.
We examine the dynamics of the translation stage of cellular protein production, in which ribosomes move uni-directionally along an mRNA strand, building amino acid chains as they go. We describe the system using a timed event graph-a class of Petri net useful for studying discrete events, which have to satisfy constraints. We use max-plus algebra to describe a deterministic version of the mode...
متن کاملTranslation with frameshifting of ribosome along mRNA transcript
Translation is an important process for prokaryotic and eukaryotic cells to produce necessary proteins for cell growth. Numerious experiments have been performed to explore the translational properties. Diverse models have also been developed to determine the biochemical mechanism of translation. However, to simplify the majority of the existing models, the frameshifting of ribosome along the m...
متن کاملذخیره در منابع من
با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید
ژورنال
عنوان ژورنال: Frontiers in Genetics
سال: 2018
ISSN: 1664-8021
DOI: 10.3389/fgene.2018.00431